dna polymerase-in-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T80644	DNA polymerase-IN-1		Antiviral , DNA/RNA Synthesis
	DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an I...		Antiviral , DNA/RNA Synthesis
T14304	Aphidicolin		Others
	Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets D...		Others
T28918	Talviraline	Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979	HIV Protease , DNA/RNA Synthesis
	Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a variety of human cell lines, as well as in fresh human perip...		HIV Protease , DNA/RNA Synthesis
T60187	RP-6685		DNA/RNA Synthesis
	RP-6685, a highly potent and selective inhibitor of DNA polymerase theta (Polθ), manifests remarkable oral activity. With an IC 50 value of 5.8 nM in the PicoGreen assay, RP-6685 effectively hinders the enzymatic activit...		DNA/RNA Synthesis
T40834	5-Hydroxymethyl-2'-deoxycytidine	5hmdC	PARP
	5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxy...		PARP
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T14313	Apricitabine	AVX754,SPD754	HIV Protease , DNA/RNA Synthesis
	Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β a...		HIV Protease , DNA/RNA Synthesis
T3157	COH29	RNR Inhibitor COH29	DNA/RNA Synthesis
	COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i...		DNA/RNA Synthesis
T79308	DNA polymerase-IN-3		DNA/RNA Synthesis
	DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in proliferative disease research [1].		DNA/RNA Synthesis
T79922	Taq DNA polymerase		DNA/RNA Synthesis
	Taq DNA polymerase is a thermostable enzyme utilized in polymerase chain reactions (PCR) to amplify DNA sequences [1].		DNA/RNA Synthesis
T79307	DNA polymerase-IN-2		DNA/RNA Synthesis
	DNA polymerase-IN-2 (Compd 3c), a coumarin derivative, demonstrates inhibitory activity towards Taq DNA polymerase, with an IC50 value of 48.25 μM, and holds potential for application in value-added disease research [1].		DNA/RNA Synthesis
T82536	DNA polymerase-IN-4
	DNA polymerase-IN-4 (Compd 5c), a coumarin derivative, exhibits antiretroviral activity, achieving an IC50 of 134.22 μM [1].
T78637	DdTTP trisodium		DNA/RNA Synthesis
	Dideoxythymidine triphosphate trisodium (ddTTP), a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), functions as a chain-elongation inhibitor of DNA polymerase in DNA sequencing applications [1].		DNA/RNA Synthesis
T74108	DdTTP
	ddTTP, a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), serves as a chain-elongation inhibitor of DNA polymerase in DNA sequencing [1].
T28585	Ro 31-8588	Ro-31-8588
	Talviraline is a RNA-directed DNA polymerase inhibitor. HBY 097 is a highly potent inhibitor of HIV-1 replication and HIV-1 induced cell killing in a variety of human cell lines as well as in fresh human peripheral bloo...
T81249	Ru3		PARP
	Ru3 is a poly(ADP-ribose) polymerase 1 (PARP1) inhibitor that prompts apoptosis in MCF-7 cells through various mechanisms, including DNA damage induction, inhibition of DNA repair, alteration of cell cycle distribution, ...		PARP
T79923	T7 RNA polymerase		DNA/RNA Synthesis
	T7 RNA polymerase, expressed by Escherichia coli from the T7 bacteriophage RNA polymerase gene, is a highly specific enzyme utilized for in vitro transcription (IVT) of mRNA. This polymerase requires Mg 2+ and selects on...		DNA/RNA Synthesis
T28494	R-82913	NSC 637653, 9-Cl-Tibo,R 82913,R82913. 9-Cmbib
	R-82913 is a RNA-directed DNA polymerase inhibitor. R 82913 reduce 5-HT2 receptor-mediated DOI-head-shakes in mice. R82913 inhibited the replication of thirteen different strains of HIV-1 in CEM cells with a median IC50 ...
T61492	Idoxuridine hydrate
	Idoxuridine hydrate (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is a competitive inhibitor of phosphorylases. As an iodinated thymidine analogue, it effectively inhibits DNA polymerase and hinders viral replication, making i...
T37106	2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)
	2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibi...